ARKIVOC

Pd-catalyzed cross-coupling reactions exhibiting catalyst turnover numbers (TONs) exceeding one million

S Xu, NL Truex, S Mohan, E Negishi

Index: Xu, Shiqing; Truex, Nicholas L.; Mohan, Swathi; Negishi, Ei-Ichi Arkivoc, 2012 , vol. 2012, # 7 p. 242 - 252

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Abstract

Abstract Pd-catalyzed cross-coupling giving aryl–aryl, alkenyl–aryl, aryl–alkenyl, alkynyl– aryl, and alkynyl–alkenyl products exhibited ultra-high turnover numbers (TONs) of 0.7× 10 7~ 0.69× 10 9 by using organozincs generated in situ by treatment of the corresponding organolithiums with dry ZnBr2. Additionally, the hydrozirconation–Pd-catalyzed cross- coupling tandem processes via treatment of 1-alkynes with i Bu2AlH-ZrCp2Cl2 followed ...