Synlett

Generation of bromophenyllithium reagents from dibromobenzenes and addition to carbonyl and nitrile electrophiles

S Caron, NM Do

Index: Caron, Stephane; Do, Nga M. Synlett, 2004 , # 8 p. 1440 - 1442

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Citation Number: 4

Abstract

Abstract An evaluation of the mono-lithiation of all three regio-isomers of dibromobenzene using n-butylithium was performed. The resulting aryllithium reagents were added to electrophiles such as ketones, aldehydes, nitriles and amides to afford the desired benzylic