Cobalt??Catalyzed Addition Reaction of Organoboronic Acids with Aldehydes: Highly Enantioselective Synthesis of Diarylmethanols

J Karthikeyan, M Jeganmohan…

Index: Karthikeyan, Jaganathan; Jeganmohan, Masilamani; Cheng, Chien-Hong Chemistry - A European Journal, 2010 , vol. 16, # 30 p. 8989 - 8992

Full Text: HTML

Citation Number: 38

Abstract

Transition-metal-catalyzed addition of organometallic reagents to aldehydes is a key method for the synthesis of substituted secondary alcohols.[1] Various organometallic reagents, such as organomagnesium,[2]-zinc,[1, 12e–i]-lithium,[3]-silane,[4]-stannane [5] and-boron,[6] have been used in these addition reactions. Among them, organoboron reagents have gained much attention due to the advantages of air and moisture stability, low toxicity, and ...