A convenient method for synthesizing 2-aryl-3-hydroxy-4-oxo-4 H-1-benzopyrans or flavonols

A Fougerousse, E Gonzalez…

Index: Fougerousse, Andre; Gonzalez, Emmanuel; Brouillard, Raymond Journal of Organic Chemistry, 2000 , vol. 65, # 2 p. 583 - 586

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Citation Number: 72

Abstract

It has recently been demonstrated that flavonols possess antiviral, antitumoral, and/or antibiotic effects. 1, 2 They are also known for their good antioxidant properties, rendering the consumption of foods (fruits, vegetables) and beverages (tea, wine) containing these compounds highly recommended. 3, 4 Commercial flavonol samples are scarce, and to evaluate their antioxidant properties, one must efficiently synthesize pure molecules in ...

 Related Synthetic Route
Ortho-Hydroxyacetophenone Structure

118-93-4

Ortho-Hydroxyac...

Benzoyl chloride Structure

98-88-4

Benzoyl chloride

~94%

2-Acetylphenyl benzoate Structure

4010-33-7

2-Acetylphenyl ...

2-phenyl-3,7,8-tribenzoyloxy-4-oxo-4H-1-benzopyran Structure

258856-70-1

2-phenyl-3,7,8-...

~91%

3,7,8-trihydroxy-2-phenylchromen-4-one Structure

108238-51-3

3,7,8-trihydrox...

Gallacetophenone Structure

528-21-2

Gallacetophenone

~%

3,7,8-trihydroxy-2-phenylchromen-4-one Structure

108238-51-3

3,7,8-trihydrox...

N/A Structure

258856-58-5

N/A

~%

3,7,8-trihydroxy-2-phenylchromen-4-one Structure

108238-51-3

3,7,8-trihydrox...

2',3',4'-tribenzoyloxy-2-bromoacetophenone Structure

258856-61-0

2',3',4'-triben...

~%

3,7,8-trihydroxy-2-phenylchromen-4-one Structure

108238-51-3

3,7,8-trihydrox...

4-(2-(benzoyloxy)-3-oxo-3-phenylpropanoyl)-3-hydroxy-1,2-phenylene dibenzoate Structure

1027073-95-5

4-(2-(benzoylox...

~%

3,7,8-trihydroxy-2-phenylchromen-4-one Structure

108238-51-3

3,7,8-trihydrox...

2,2',3',4'-tetrabenzoyloxyacetophenone Structure

258856-65-4

2,2',3',4'-tetr...

~%

3,7,8-trihydroxy-2-phenylchromen-4-one Structure

108238-51-3

3,7,8-trihydrox...

N/A Structure

258856-69-8

N/A

~88%

3,7-dihydroxyflavone Structure

492-00-2

3,7-dihydroxyflavone

2,4-Dihydroxyacetophenone Structure

89-84-9

2,4-Dihydroxyac...

~%

3,7-dihydroxyflavone Structure

492-00-2

3,7-dihydroxyflavone

1-(2,4-Bis(benzoyloxy)phenyl)ethanone Structure

66832-97-1

1-(2,4-Bis(benz...

~%

3,7-dihydroxyflavone Structure

492-00-2

3,7-dihydroxyflavone

2,2',4'-tribenzoyloxyacetophenone Structure

258856-64-3

2,2',4'-tribenz...

~%

3,7-dihydroxyflavone Structure

492-00-2

3,7-dihydroxyflavone

2',4'-dibenzoyloxy-2-bromoacetophenone Structure

258856-60-9

2',4'-dibenzoyl...

~%

3,7-dihydroxyflavone Structure

492-00-2

3,7-dihydroxyflavone

N/A Structure

1027955-57-2

N/A

~%

3,7-dihydroxyflavone Structure

492-00-2

3,7-dihydroxyflavone

Ortho-Hydroxyacetophenone Structure

118-93-4

Ortho-Hydroxyac...

p-Anisoyl chloride Structure

100-07-2

p-Anisoyl chloride

~96%

Benzoic acid,4-methoxy-, 2-acetylphenyl ester Structure

5445-86-3

Benzoic acid,4-...

2-(4'-methoxyphenyl)-3-benzoyloxy-4-oxo-4H-1-benzopyran Structure

258856-71-2

2-(4'-methoxyph...

~88%

4'-Methoxyflavonol Structure

6889-78-7

4'-Methoxyflavonol


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