Metabolism-based synthesis, biologic evaluation and SARs analysis of O-methylated analogs of quercetin as thrombin inhibitors

ZH Shi, NG Li, YP Tang, JP Yang, JA Duan

Index: European Journal of Medicinal Chemistry, , vol. 54, p. 210 - 222

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Citation Number: 27

Abstract

... European Journal of Medicinal Chemistry. ... b Department of Medicinal Chemistry, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210046, China; c Department of Organic Chemistry, China ... atm), THF/EtOH, 12 h, 91%; (i) MeI, K 2 CO 3 , DMF, 25 °C, 12 h, 92%; (j) Pd/C ...