The Journal of organic chemistry

2-Chloro-2, 2-difluoroacetophenone: a non-ODS-based difluorocarbene precursor and its use in the difluoromethylation of phenol derivatives

L Zhang, J Zheng, J Hu

Index: Journal of Organic Chemistry, , vol. 71, # 26 p. 9845 - 9848

Full Text: HTML

Citation Number: 45

Abstract

... The Journal of Organic ... reaction tube was sealed, and the mixture was heated to 80 °C and stirred for 4 h. Then the mixture was extracted with Et 2 O (25 mL × 3), and the combined organic phase was ... 19 F NMR: δ −82.6 (dt, J = 73.5 Hz, 7 Hz, 2F), −116.7 (m, 1F), −120.2 (m, 1F). ...