Tetrahedron Letters

Chemoselective O-tert-butoxycarbonylation of phenols using 6, 7-dimethoxyisoquinoline as a novel organocatalyst

Y Saito, Y Yoshimura, H Takahata

Index: Saito, Yukako; Yoshimura, Yuichi; Takahata, Hiroki Tetrahedron Letters, 2010 , vol. 51, # 52 p. 6915 - 6917

Full Text: HTML

Citation Number: 4

Abstract

Among the carbonic acid derivatives used as protecting groups, tert-butyl carbonates and carbamates are of great importance in organic chemistry due to both their resistance to nucleophilic reagents and ease of removal under specific conditions. 1 We previously reported on the use of 1-tert-butoxy-2-tert-butoxycarbonyl-1,2-dihydroisoquinoline (BBDI) prepared by the reaction of isoquinoline with Boc 2 O as a novel and chemoselective tert-butoxycarbonylation ...