Tetrahedron

Ring-closing metathesis for the synthesis of 2H-and 4H-chromenes

WAL van Otterlo, EL Ngidi, S Kuzvidza, GL Morgans…

Index: Van Otterlo, Willem A.L.; Ngidi, E. Lindani; Kuzvidza, Samuel; Morgans, Garreth L.; Moleele, Simon S.; De Koning, Charles B. Tetrahedron, 2005 , vol. 61, # 42 p. 9996 - 10006

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Citation Number: 78

Abstract

Six 4H-chromenes were synthesized from substituted phenols using vinylstannylation and ring-closing metathesis (RCM) as key steps. In addition, a different approach involving amongst other steps, an aryl allyl isomerization and RCM afforded a set of seven 2H- chromenes from phenolic precursors.