Tetrahedron letters

An efficient method for hydrolysis of N-monosubstituted amides via acetoxypivalimides

T Tsunoda, O Sasaki, S Itô

Index: Tsunoda, Tetsuto; Sasaki, Osamu; Ito, Sho Tetrahedron Letters, 1990 , vol. 31, # 5 p. 731 - 734

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Citation Number: 9

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Various N-monosubstituted carboxamides were efficiently hydrolyzed in two steps through acetoxypivalimides. The method can he applied to a wide range of amides without racemization of α-position of the acyl groups. The amines can also be recovered.

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