Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... An end-game strategy towards the synthesis of apoptolidin has been demonstrated in a model study, in which the C(1)–C(15) fragment was successfully assembled using three consecutive Suzuki coupling reactions. ... The preparation of boronate 5 started with trimethylsilyl ...