Synthesis of A-79175: a second generation 5-lipoxygenase inhibitor

…, HE Morton, SR Chemburkar, HH Patel, A Thomas…

Index: Dickman, Daniel A.; Ku, Yi-Yin; Morton, Howard E.; Chemburkar, Sanjay R.; Patel, Hemantkumar H.; Thomas, Albert; Plata, Daniel J.; Sawick, David P. Tetrahedron Asymmetry, 1997 , vol. 8, # 11 p. 1791 - 1795

Full Text: HTML

Citation Number: 12

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A convergent, high yielding, and scalable synthesis of A-79175, with a key step involving a mild and efficient CuPd catalyzed coupling reaction of a terminal acetylene with a substituted 2-iodofuran is discussed. ... A synthesis of A-79175, with a key step involving an efficient ...