Efficient synthesis of polysubstituted acylguanidines and guanylureas

AR Katritzky, BV Rogovoy, X Cai…

Index: Augustin, M.; Richter, M.; Salas, S. Journal fuer Praktische Chemie (Leipzig), 1980 , vol. 322, # 1 p. 55 - 68

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Citation Number: 20

Abstract

... Volume: Page: ... Journal ... All the acyl-substituted (benzotriazole-1-yl)carboximidamides gave the desired guanidines 7a−d,k−o in good to excellent yields in reactions with primary and secondary alkylamines, anilines, and α-amino esters. ...

 Related Synthetic Route
N-Benzoyliminodithiokohlensaeuredimethylester Structure

24786-18-3

N-Benzoyliminod...

guanidine Structure

113-00-8

guanidine

~60%

4-methylsulfanyl-6-phenyl-1,3,5-triazin-2-amine Structure

14945-93-8

4-methylsulfany...

N-Benzoylamino-dithiokohlensaeuremethylester Structure

21406-30-4

N-Benzoylamino-...

~%

4-methylsulfanyl-6-phenyl-1,3,5-triazin-2-amine Structure

14945-93-8

4-methylsulfany...

N-Benzoylamino-dithiokohlensaeuremethylester Structure

21406-30-4

N-Benzoylamino-...

~%

N-(N,N'-diethylcarbamimidoyl)benzamide Structure

74074-32-1

N-(N,N'-diethyl...

N-Benzoyliminodithiokohlensaeuredimethylester Structure

24786-18-3

N-Benzoyliminod...

Ethylamine Structure

75-04-7

Ethylamine

~51%

N-(N,N'-diethylcarbamimidoyl)benzamide Structure

74074-32-1

N-(N,N'-diethyl...

N-(bis-(methylsulfanyl)methylene)-4-methoxybenzamide Structure

74074-23-0

N-(bis-(methyls...

Benzylamine Structure

100-46-9

Benzylamine

~63%

N-(N,N'-dibenzylcarbamimidoyl)-4-methoxybenzamide Structure

74074-33-2

N-(N,N'-dibenzy...

N-(3-chloro-2-methylphenyl)-7-methoxy-2-oxochromene-3-carboxamide Structure

7047-18-9

N-(3-chloro-2-m...

~%

N-(N,N'-dibenzylcarbamimidoyl)-4-methoxybenzamide Structure

74074-33-2

N-(N,N'-dibenzy...

N-(3-chloro-2-methylphenyl)-7-methoxy-2-oxochromene-3-carboxamide Structure

7047-18-9

N-(3-chloro-2-m...

~%

N-(N,N'-dicyclohexylcarbamimidoyl)-4-methoxybenzamide Structure

74074-34-3

N-(N,N'-dicyclo...

N-(bis-(methylsulfanyl)methylene)-4-methoxybenzamide Structure

74074-23-0

N-(bis-(methyls...

Cyclohexylamine Structure

108-91-8

Cyclohexylamine

~92%

N-(N,N'-dicyclohexylcarbamimidoyl)-4-methoxybenzamide Structure

74074-34-3

N-(N,N'-dicyclo...

dimethyl (2-chlorobenzoyl)carbonimidodithioate Structure

74074-22-9

dimethyl (2-chl...

isopropylamine Structure

75-31-0

isopropylamine

~43%

2-chloro-N-[N,N'-di(propan-2-yl)carbamimidoyl]benzamide Structure

74074-35-4

2-chloro-N-[N,N...

N-[2-chloro-5-(trifluoromethyl)phenyl]-7-methoxy-2-oxochromene-3-carboxamide Structure

7047-16-7

N-[2-chloro-5-(...

~%

2-chloro-N-[N,N'-di(propan-2-yl)carbamimidoyl]benzamide Structure

74074-35-4

2-chloro-N-[N,N...

N-Benzoyliminodithiokohlensaeuredimethylester Structure

24786-18-3

N-Benzoyliminod...

isopropylamine Structure

75-31-0

isopropylamine

~47%

N-[N,N'-di(propan-2-yl)carbamimidoyl]benzamide Structure

74074-31-0

N-[N,N'-di(prop...

N-Benzoylamino-dithiokohlensaeuremethylester Structure

21406-30-4

N-Benzoylamino-...

~%

N-[N,N'-di(propan-2-yl)carbamimidoyl]benzamide Structure

74074-31-0

N-[N,N'-di(prop...


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