Synthesis of. beta.-keto 1, 3-dithianes from acetylenic ketones

BC Ranu, S Bhar, R Chakraborti

Index: Ranu, Brindaban C.; Bhar, Sanjay; Chakraborti, Ratna Journal of Organic Chemistry, 1992 , vol. 57, # 28 p. 7349 - 7352

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Citation Number: 41

Abstract

reaction entry R1 R2 time (h) yield"(%) a i-Pr H 4 lob b Ph H 5 82'c 4-OMe-C6H4 H 5 85'd 3, 4-(OMe) 2CBH3 H 5 8 P e i-Pr CHZOCHS 5 80b f Ph CH20CH3 6 15b a All yields refer to pure isolated producta, fully characterized by IR and'H NMR. bThe reaction was carried out without solvent.'The reaction was run in CH2C12. approach for the synthesis of@-keto l, &dithianas through double Michael addition of l, &propanedithiol to a, O-acetylenic ...