e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

5, 5-Disubstituted hydantoins: syntheses and anti-HIV activity

RN Comber, RC Reynolds, JD Friedrich…

Index: Journal of Medicinal Chemistry, , vol. 35, # 19 p. 3567 - 3572

Full Text: HTML

Citation Number: 72

Abstract

... Manuscript in preparation. 1986, 111, 1001-1002. 0022-2623/92/1835-3561$03.00/0 0 1992 American Chemical Society Page 2. 3568 Journal of Medicinal Chemistry, 1992, Vol. 35, No. 19 Comber et al. Table I. Compounds Studied antiviral activitv (uM) - .I . ...

5,5-Bis(((phenylmethyl)thio)methyl)-2,4-imidazolidinedione Structure

5,5-Bis(((pheny...

~%

5,5-bis(pyridin-3-ylmethylsulfanylmethyl)imidazolidine-2,4-dione Structure

5,5-bis(pyridin...

3-Chloromethylpyridinehydrochloride Structure

3-Chloromethylp...

5,5-bis(sulfanylmethyl)imidazolidine-2,4-dione Structure

5,5-bis(sulfany...

~%

5,5-bis(pyridin-3-ylmethylsulfanylmethyl)imidazolidine-2,4-dione Structure

5,5-bis(pyridin...

5,5-Bis(((phenylmethyl)thio)methyl)-2,4-imidazolidinedione Structure

5,5-Bis(((pheny...

~%

methyl 4-[[4-[(4-methoxycarbonylphenyl)methylsulfanylmethyl]-2,5-dioxoimidazolidin-4-yl]methylsulfanylmethyl]benzoate Structure

methyl 4-[[4-[(...

Methyl 4-(bromomethyl)benzoate Structure

Methyl 4-(bromo...

5,5-bis(sulfanylmethyl)imidazolidine-2,4-dione Structure

5,5-bis(sulfany...

~%

methyl 4-[[4-[(4-methoxycarbonylphenyl)methylsulfanylmethyl]-2,5-dioxoimidazolidin-4-yl]methylsulfanylmethyl]benzoate Structure

methyl 4-[[4-[(...

5,5-Bis(((phenylmethyl)thio)methyl)-2,4-imidazolidinedione Structure

5,5-Bis(((pheny...

~18%

5,5-bis(benzylsulfanylmethyl)imidazolidine-2,4-dithione Structure

5,5-bis(benzyls...

5,5-Bis(((phenylmethyl)thio)methyl)-2,4-imidazolidinedione Structure

5,5-Bis(((pheny...

~%

5,5-bis(naphthalen-1-ylmethylsulfanylmethyl)imidazolidine-2,4-dione Structure

5,5-bis(naphtha...

5,5-bis(sulfanylmethyl)imidazolidine-2,4-dione Structure

5,5-bis(sulfany...

1-Chloromethyl naphthalene Structure

1-Chloromethyl ...

~%

5,5-bis(naphthalen-1-ylmethylsulfanylmethyl)imidazolidine-2,4-dione Structure

5,5-bis(naphtha...