A novel synthesis of 2-alkylthiobenzothiazoles and 2-alkylthiobenzoxazoles

Y Yu, Z Li, L Jiang

Index: Yu, Yanfei; Li, Zhengning; Jiang, Lan Phosphorus, Sulfur and Silicon and the Related Elements, 2012 , vol. 187, # 5 p. 632 - 640

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Citation Number: 2

Abstract

3H-Benzothiazole-2-thione and 3H-benzoxazole-2-thione were selectively S-alkylated by use of O-alkylisoureas as the alkylating reagents. The reactions could be performed under mild reaction conditions in short reaction times, and high yields were obtained using O-primary-alkylisoureas, whereas low yields were obtained with sec- and tert-alkylisoureas. ... 3H-Benzothiazole-2-thione and 3H-benzoxazole-2-thione were selectively S-alkylated ...