e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Studies on tertiary amine oxides. LXVIII.. Reactions of aromatic N??oxides with 2??substituted 2??oxazolin??5??ones in the presence of acetic anhydride
MM Yousif, S Saeki, M Hamana
Index: Yousif, M. Mohammed; Saeki, S.; Hamana, M. Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 1029 - 1034
Abstract Quinoline l-oxides 1a-f readily react with 2-phenyl-and 2-methyl-2-oxazolin-5-ones, 2a and 2b, in the presence of acetic anhydride to afford 2-substituted 4-(2-quinolyl)-2- oxazolin-5-ones 3a-h in good yields. Hydrolysis of 3a-f with 10% hydrochloric acid under refluxing conditions gives the corresponding 2-amino-methylquinoline dihydrochlorides 5a- e or monohydrochloride 5f also in good yields. Similar results are obtained from reactions ...
