Tetrahedron letters

Acid catalyzed reactions of α, β-unsaturated aldehydes and ethyl diazoacetate

B Branstetter, MM Hossain

Index: Branstetter, Bryan; Hossain, M. Mahmun Tetrahedron Letters, 2006 , vol. 47, # 2 p. 221 - 223

Full Text: HTML

Citation Number: 15

Abstract

The formation of cyclopropanes from α, β-unsaturated aldehydes and diazo compounds has been a rather challenging goal due to the extremely reactive aldehyde starter. Herein, our group reports the first formation of ethyl 2-formyl-1-cyclopropanecarboxylate in 100% yield from the acid catalyzed reaction between acrolein and ethyl diazoacetate (EDA).