Acid??Catalyzed Cascade Reactions of Enaminones with Aldehydes: C–H Functionalization To Afford 1, 4??Dihydropyridines

J Yang, C Wang, X Xie, H Li, Y Li

Index: Yang, Jingyu; Wang, Chengyu; Xie, Xin; Li, Hongfeng; Li, Yanzhong European Journal of Organic Chemistry, 2010 , # 22 p. 4189 - 4193

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Citation Number: 25

Abstract

Abstract An efficient acid-catalyzed approach to the synthesis of functional 1, 4- dihydropyridines from the reaction of readily available enaminones with aldehydes has been developed. This methodology was realized by a cascade reaction involving first formation of divinylmethanes and subsequent intramolecular cyclization.

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