e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Tetrahedron letters
Transition state stucture and frontier orbital influence on the cycloaddition reactions of 2, 5-dimethyl-3, 4-dimethylenethiophene with styrenes and benzaldehydes
Abstract The biradical 2, 5-dimethyl-3, 4-dimethylenethiophene reacts with styrenes and benzaldehydes to give fused cycloadducts. The effect of substituents on the efficiency of the benzaldehyde trapping reaction resembles that of normal electron-demand Diels-Alder