Synthesis and mitogenic activity of new imidazo [2, 1-b] thiazoles

A Andreani, M Rambaldi, A Locatelli…

Index: Andreani; Rambaldi; Locatelli; Isetta European Journal of Medicinal Chemistry, 1991 , vol. 26, # 3 p. 335 - 337

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Citation Number: 18

Abstract

Abstract Eight new imidazo [2, 1-b] thiazoles were synthesized in order to evaluate their ability to stimulate the proliferation of thymic lymphocytes. The 2-chloro (5–8) proved more active than the 2, 3-dimethyl derivatives (1–4): in particular compounds 6 and 7 were more active than levamisole.