Journal of the American Chemical Society

Solid-phase synthesis of positively charged deoxynucleic guanidine (DNG) tethering a Hoechst 33258 analogue: Triplex and duplex stabilization by simultaneous …

PM Reddy, TC Bruice

Index: Reddy, Putta Mallikarjuna; Bruice, Thomas C. Journal of the American Chemical Society, 2004 , vol. 126, # 12 p. 3736 - 3747

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Citation Number: 23

Abstract

Deoxynucleic guanidine (DNG), a DNA analogue in which positively charged guanidine replaces the phosphodiester linkages, tethering to Hoechst 33258 fluorophore by varying lengths has been synthesized. A pentameric thymidine DNG was synthesized on solid ...

~76%

Synthesis and cellular uptake of a fluorescently labeled cyc...

[Caldarelli, Sergio; Depecker, Geoffrey; Patino, Nadia; Di Giorgio, Audrey; Barouillet, Thibault; Doglio, Alain; Condom, Roger Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 17 p. 4435 - 4438]