Abstract: The stepwise synthesis of peptides by the initial attachment of an amino acid r- butyloxycarbonylhydrazide through its a-amino group to a polystyrene resin was investigated. The resin-amino acid azide was generated quantitatively and coupled with another amino acid t-butyloxycarbonylhydrazide. The peptide chain was elongated by further azige couplings. Finally, the C-terminal amino acid was added as a t-butyl ester. ...
