Combined directed Ortho-, remote-metalation and cross-coupling strategies. Concise syntheses of the kinamycin biosynthetic grid antibiotics phenanthroviridin …

S Mohri, M Stefinovic, V Snieckus

Index: Mohri, Shin-Ichiro; Stefinovic, Marijan; Snieckus, Victor Journal of Organic Chemistry, 1997 , vol. 62, # 21 p. 7072 - 7073

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Citation Number: 84

Abstract

The kinamycins constitute a class of polyketidederived1 antitumor antibiotics first isolated from Streptomyces murayamaensis, 2 in which the already considerable biosynthetic and synthetic interest has been accelerated by their recent structural revision from N- ...