e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Tetrahedron
Syntheses of 3b, 4, 6, 7-Tetrahydro-5h, 9h-pyrazino [2, 1-c] phyrolo [1, 2-a][1, 4] benzodiazepine, a valuable precursor of potential central nervous system agents
Two alternative routes to 3b, 4, 6, 7-tetrahydro-4H, 9H-pyrazino [2, 1-c] pyrrolo [1, 2-a][1, 4] benzodiazepine, a useful intermediate for the synthesis of potential antidepressant agents, are described. Though following conceptually different synthetic approaches, both procedures lead to the title compound in a simple and profitable way.
![5,6-dihydro-5-benzyloxycarbonylaminoacetyl-4-ethoxycarbonyl-4H-pyrrolo[1,2-a][1,4]benzodiazepine Structure](https://image.chemsrc.com/caspic/043/122485-07-8.png)
