Bulletin of the Chemical Society of Japan

NAD (P)+–NAD (P) H Models. 64. The Quantitative Elucidation of the Mechanistic Aspects in the Silica Gel-Catalyzed Reduction of α, β-Unsaturated Carbonyl …

S Yasui, M Fujii, A Ohno

Index: Yasui, Shinro; Fujii, Masayuki; Ohno, Atsuyoshi Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 11 p. 4019 - 4026

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Citation Number: 18

Abstract

Eight α, β-unsaturated carbonyl compounds, 1-(2′-or 4′-substituted phenyl)-3-phenyl-2- propen-1-ones (2′-or 4′-substituted chalcones), were subjected to the reduction by an NAD (P) H model in the presence of silica gel in benzene. All of these afforded quantitatively the corresponding saturated carbonyl compounds, whereas no 1, 2-reduction took place. For 2′-methoxy, 4′-methyl, 4′-bromo, and 4′-nitro derivatives as well as the ...