Jadomycins A and B are unique members of the angucycline family of natural products with the unusual 8H-benz [b] oxazolo [3, 3-f]-phenanthridine ring system (Scheme 1). Both jadomycins A and B are produced by the Gram-positive soil bacteria Streptomyces venezuelae ISP5230 under specific nutrient and environmental stress.[1] They display important bioactivities, including antitumor, antimicrobial, anti-viral, as well as, aurora-B ...
