Tetrahedron letters

Highly regio and stereoselective preparation of Z silyl enol ethers and Z enol esters from ketones via manganese enolates

G Cahiez, B Figadère, P Cléry

Index: Cahiez, Gerard; Figadere, Bruno; Clery, Patrick Tetrahedron Letters, 1994 , vol. 35, # 34 p. 6295 - 6298

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Citation Number: 24

Abstract

Abstract Mn-enolates are easily and quantitatively obtained under mild conditions (THF,− 10 C to rt, 1h) by treatment of ketones with aromatic Mn-amides such as Ph (Me) NMnZ. They allow to prepare Z silyl enol ethers and Z enol esters in high yields and with an excellent regio-and stereoselectivity (kinetic product:≥ 99%, Z/E: Full-size image (< 1 K)