A new method for the stereoselective synthesis of α-and β-glycosylamines using the Burgess reagent

KC Nicolaou, SA Snyder, AZ Nalbandian…

Index: Nicolaou; Snyder, Scott A.; Nalbandian, Annie Z.; Longbottom, Deborah A. Journal of the American Chemical Society, 2004 , vol. 126, # 20 p. 6234 - 6235

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Citation Number: 55

Abstract

Although glycosylamines constitute an important group of carbohydrates from the standpoint of biology and medicine, methods for their synthesis typically lack substrate generality and/or result in variable stereoselectivity, especially in complex contexts. In this communication, we report an operationally simple method for the synthesis of both α-and β- glycosylamines using the Burgess reagent that overcomes many of these limitations in a ...