Synthesis and biological evaluation of N-substituted quinolinimides, as potential ligands for in vivo imaging studies of δ-opioid receptors

T Bourdier, G Poisnel, M Dhilly, J Delamare…

Index: Lever, John R.; Kinter, Chris M.; Ravert, Hayden T.; Musachio, John L.; Mathews, William B.; Dannals, Robert F. Journal of Labelled Compounds and Radiopharmaceuticals, 1995 , vol. 36, # 2 p. 137 - 146

Full Text: HTML

Citation Number: 7

Abstract

... Among them, compound 1 represents the most promising compound with an affinity of 6 nM (IC 50 δ) for the cloned human DOP−R. From this new ... 5.08 (dd, J = 9.6 Hz, J = 5.0 Hz, 1H), 4.40 (dt, J = 47.0 Hz, J = 5.5 Hz, 2H), 4.05−3.85 (m, 3H), 3.70−3.50 (m, 1H), 2.60 (t, J = 7.4 ...