e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Two-step synthesis of (. gamma.,. gamma.-difluoroallyl) carbonyl compounds via addition of 1, 1, 2-trichloro-2, 2-difluoroethyl radical to silyl enol ethers followed by …
Fluorine-containing olefins are important synthetic intermediates for the biologically active compounds.'We have recently reported the transition metal induced synthesis of trifluoromethylated unsaturated carbonyl compounds. 2 In the reaction, CFsCCl $ radical is generated from CF3CC13 by single electron transfer from a Cu (1) or Ru (I1) salt and is used as the reactive intermediate for the addition to trimethylsilyl enol ethers to give ...
