Synthesis of 3??substituted??4??methyl??5??acetyl??4??thiazoline??2??thione

JJ D'Amico, FG Bollinger…

Index: D'Amico, John J.; Bollinger, Frederic G.; Freeman, John J. Journal of Heterocyclic Chemistry, 1986 , vol. 23, p. 101 - 104

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Citation Number: 4

Abstract

Abstract The reaction of various potassium salts [RNHC (= S) SK, R= N (CH 3) 2, morpholino, piperidino, and hexahydro-1-(1H)-azepinyl] with 3-chloro-2, 4-pentanedione in ethanol at 25–30 afforded the 1-acetylacetonyl substitutedaminodithiocarbamates 1–4 [RNHC (= S) SCH (COCH 3) 2]. Under refluxing conditions, the same reactants gave the heterocyclic compounds 5–8. Possible mechanism and supporting ir, nmr and mass ...