Journal of the American Chemical Society

Pd-Catalyzed Intramolecular Aminohydroxylation of Alkenes with Hydrogen Peroxide as Oxidant and Water as Nucleophile

H Zhu, P Chen, G Liu

Index: Zhu, Bo; Yan, Lin; Pan, Yuanhang; Lee, Richmond; Liu, Hongjun; Han, Zhiqiang; Huang, Kuo-Wei; Tan, Choon-Hong; Jiang, Zhiyong Journal of Organic Chemistry, 2011 , vol. 76, # 16 p. 6894 - 6900

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Citation Number: 36

Abstract

A palladium-catalyzed intramolecular aminohydroxylation of alkenes was developed, in which H2O2 was applied as the sole oxidant. A variety of related alkyl alcohols could be successfully obtained with good yields and excellent diastereoselectivities, which directly