Reaction of Basic Nitriles with Hydrogen Chloride

FF Blicke, AJ Zambito, RE Stenseth

Index: Blicke,F.F. et al. Journal of Organic Chemistry, 1961 , vol. 26, p. 1826 - 1831

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Citation Number: 7

Abstract

It has been~ hown~-~ that a-phenyl-and ala-diphenyl-y-dialkylaminobutyronitriles, when heated with concentrated hydrochloric or hydrobromic acid, were converted into salts of l- alkyl-2-imino-3-phenyl (or 3, 3-diphenyl) pyrrolidines or the corresponding 2-pyrrolidone. It was found7 that when ala-diphenyl-y-diethylaminobutyronitrile (I) 8 was heated at 270- 275'in a stream of hydrogen chloride, 1-ethyl-2-imino-3, 3-diphenylpyrrolidine ...