N-(a-Alkoxyalky1) amides are of importance both in natural product chemistry and in industrial synthesis. Pederin, a toxic principle isolated from Paedelus fuscipes curt, contains an N-(a-methoxyalky1) amide structural feature, 2 and N-(a-alkoxyalky1) amide functionalities also occur in a number of synthetic herbicide^.^ N-(a-Alkoxyalky1) amides are useful synthetic intermediates and have participated in the amidoalkylations of aromatics ...