Aryl sulfonamido indane inhibitors of the Kv1. 5 ion channel

MF Gross, S Beaudoin, G McNaughton-Smith…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 10 p. 2849 - 2853

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Citation Number: 39

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... 2 AF is a major public health concern and there is a growing medical need to reduce the occurrence of AF with drugs that lack the ventricular proarrhythmic side effects (eg, torsades de pointes) associated with currently used ...