" Hydrophobic" binding of water-soluble guests by high-symmetry, chiral hosts. An electron-rich receptor site with a general affinity for quaternary ammonium …

MA Petti, TJ Shepodd, RE Barrans…

Index: Petti,M.A.; Shepold,T.J.; Barrans,R.E. Journal of the American Chemical Society, 1988 , vol. 110, p. 6825

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Citation Number: 192

Abstract

Abstract: Several members of a new class of water-soluble macrocycles with well-defined, hydrophobic binding sites have been prepared and their binding properties analyzed. These hosts are built up from ethenoanthracene units and exist in meso (C,) and d, l (D,) forms. The latter have been synthesized enantiomerically pure, the key step being a highly selective asymmetric Diels-Alder reaction. Several of these hosts display a strong and fairly general ...