Synthesis

Synthesis and utility of α-methoxy phosphonates with a 1, 3, 2-dioxaphosphorinane ring

M Chakravarty, B Srinivas, C Muthiah, KCK Swamy

Index: Chakravarty, Manab; Srinivas; Muthiah; Kumara Swamy Synthesis, 2003 , # 15 p. 2368 - 2372

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Citation Number: 17

Abstract

Abstract Synthesis of several α-methoxy phosphonates with the phosphorus as a part of 1, 3, 2-dioxaphosphorinane ring by the simple reaction of (OCH 2 CMe 2 CH 2 O) PCl with acetals is described. Analogous methoxy phosphonates using (±)(C 20 H 12 O 2) PCl were also synthesized using the same route. Utility of these phosphonates in the synthesis of vinyl ethers via the Horner-Wadsworth-Emmons [HWE] reaction is demonstrated.