Synthesis of 2H-isoindole-4, 7-diones by 1, 3-dipolar addition of oxazolium 5-oxides to 1, 4-quinones

…, LD Moore Jr, WL Whitter, SL Council…

Index: Myers, John A.; Moore, Lloyd D.; Whitter, Willie L.; Council, Samuel L.; Waldo, Rosalyn M.; et al. Journal of Organic Chemistry, 1980 , vol. 45, # 7 p. 1202 - 1206

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Citation Number: 17

Abstract

3-Methyl-2, 4-diphenyloxazolium &oxide, formed by dehydrative cyclization of N-methyl-N- benzoyl-C-phenylglycine, combines with 1, 4-quinones to produce 2H-isoindole-4, 7-diones in moderate yields. Conversion of other N-acyl amino acids to the corresponding less ...