Biologically active hydroximoyl chlorides as anti-fungal agents

…, S Shafi, PP Singh, NA Qazi, SD Sawant…

Index: Ismail, Tabasum; Shafi, Syed; Singh, Parvinder Pal; Qazi, Naveed Ahmed; Sawant, Sanghapal D.; Ali, Intzar; Khan, Inshad Ali; Kumar; Qazi, Ghulam Nabi; Alam, M. Sarwar Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2008 , vol. 47, # 5 p. 740 - 747

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Citation Number: 12

Abstract

Abstract: Several oximes and oxime ethers have been developed as antimicrobial agents. A series of chlorooximes (hydroximoyl chlorides) have been synthesized and tested for antifungal activity under in-vitro conditions against Candida albicans, Candida parapsilosis, Candida glabrata, Candida krusei, Aspergillus fumigatus, Aspergillus flavus and Aspergillus niger. The derived antifungal activity has been compared with the corresponding oximes. ...