Tetrahedron

Transfer hydrogenolysis: an improved synthesis of (R)-(-)-α-Methyl Histamine

RJ Friary, P Mangiaracina, M Nafissi, SC Orlando…

Index: Friary, Richard J.; Mangiaracina, Pietro; Nafissi, Mehdi; Orlando, Steven C.; Rosenhouse, Stanley; et al. Tetrahedron, 1993 , vol. <10> 49, p. 1993 - 1996

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Citation Number: 5

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Ammonium formate in the presence of palladium on carbon in methanol reacted with (S)-(+)4 -(2-Amino-3-chloropropyl)-imidazole to give optically pure (R)-(−)-α-methyl histamine at atmospheric pressure. ... R-(-)-α-methyl histamine was prepared via a new and convenient method.