Aluminium (III) trifluoromethanesulfonate as an efficient catalyst for the intramolecular hydroalkoxylation of unactivated olefins: experimental and theoretical …

L Coulombel, M Rajzmann, JM Pons…

Index: Coulombel, Lydie; Rajzmann, Michel; Pons, Jean-Marc; Olivero, Sandra; Dunach, Elisabet Chemistry - A European Journal, 2006 , vol. 12, # 24 p. 6356 - 6365

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Citation Number: 88

Abstract

Abstract The Al (OTf) 3-catalyzed cycloisomerization of unactivated unsaturated alcohols was studied from experimental and theoretical points of view. A series of cyclic ethers was obtained in excellent yields and regioselectivities. This catalyst system provides one of the most straightforward routes to cyclic ethers with Markovnikov-type regioselectivity under mild conditions. Theoretical and NMR studies were carried out in order to better determine the ...