Synthesis of furo [2, 3??b] pyridine

JW McFarland, RP Wollerman…

Index: McFarland,J.W. et al. Journal of Heterocyclic Chemistry, 1971 , vol. 8, p. 735 - 738

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Citation Number: 3

Abstract

Abstract Two routes were employed to synthesize unsubstituted furo [2, 3-b] pyridine (IV). The first method started with ethyl 5-aminofuro [2, 3-b] pyridine-2-carboxylate (1) and involved successive deamination, hydrolysis, and decarboxylation. The second method began with 5-nitrofuro [2, 3-b]-pyridine-2-carboxylic acid (V) and consisted of successive decarboxylation, reduction, and deamination reactions.