Journal of medicinal chemistry

Preparation of substituted phenethyl alcohols and a study of their bacteriostatic action in Escherichia coli B1

EZ Khafagy, JP Lambooy

Index: Khafagy,E.Z.; Lambooy,J.P. Journal of Medicinal Chemistry, 1966 , vol. 9, p. 936 - 940

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Citation Number: 13

Abstract

2, B-Dimethoxyphenethyl alcohol was synthesized from m-dimethoxybenzene. Phenyllithium was used to int'roduce the lithium atom into the ring between the methoxy groups to yield 2, 6-dimethoxyphenyllithium. The remainder of the synthetic sequence was the same as that, used for the preparation of 0-, nz-, and pmethoxyphenethyl alcohols outlined above. 0-and p-hydroxyphenethyl alcohols were prepared from the ...