Synthesis, determination of absolute configuration, and biological evaluation of spiro-fused thiadiazoline inhibitors of kinesin spindle protein (KSP)

AR Angeles, L Yang, C Dai, A Brunskill, AD Basso…

Index: Tetrahedron Letters, , vol. 51, # 48 p. 6236 - 6239

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Citation Number: 7

Abstract

... Tetrahedron Letters. Volume 51, Issue 48, 1 December 2010, Pages 6236–6239. ... method employed toward the preparation of dihydrochromanones 12a–b involved an alkylation of phenols 8a–b with β-propiolactone to afford, as the principal product (in 48% yield), carboxylic ...