Rapid synthesis of 1, 3, 5-substituted 1, 2, 4-triazoles from carboxylic acids, amidines, and hydrazines

GM Castanedo, PS Seng, N Blaquiere…

Index: Xu, Yingju; McLaughlin, Mark; Bolton, Emily N.; Reamer, Robert A. Journal of Organic Chemistry, 2010 , vol. 75, # 24 p. 8666 - 8669

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Citation Number: 38

Abstract

... The Journal of Organic ... this table are isolated yields after silica gel chromatography or reverse phase HPLC.1,3,5- substituted regioisomers were confirmed by 15 N HMBC and ... 1 H NMR (500 MHz, DMSO) δ 8.05 (d, J = 7.0 Hz, 2H), 7.62 (d, J = 7.7 Hz, 2H), 7.51−7.40 (m, 3H), 7.13 ...