Efficient protocol for reductive amination of aldehydes and ketones with sodium borohydride in an ionic liquid/H2O system

…, V Naveen Kumar, R Srinivasa Rao…

Index: Nagaiah; Kumar, V. Naveen; Rao, R. Srinivasa; Reddy; Narsaiah; Yadav Synthetic Communications, 2006 , vol. 36, # 22 p. 3345 - 3352

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Citation Number: 13

Abstract

Abstract The imines were generated in situ from carbonyl compounds and amines, which undergo smooth reduction with sodium borohydride in an ionic liquid/H2O solvent system. The reaction conditions were very mild and neutral to afford the corresponding highly functionalized amines in excellent yields. IICT Communication No. 041013.