An intramolecular organocatalytic cyclopropanation reaction

N Bremeyer, SC Smith, SV Ley…

Index: Bremeyer, Nadine; Smith, Stephen C.; Ley, Steven V.; Gaunt, Matthew J. Angewandte Chemie - International Edition, 2004 , vol. 43, # 20 p. 2681 - 2684

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Citation Number: 141

Abstract

Catalytic processes that form functionalized cyclic molecules represent a key transformation for synthetic organic chemistry.[1, 2] Recently, a number of organocatalytic processes have emerged that often provide excellent levels of both enantioand diastereocontrol for the synthesis of cyclic molecules.[3, 4] Our recent studies have identified the utility of ammonium ylides for carbon–carbon bond formation. Herein we describe the development of a new ...