Tetrahedron: Asymmetry

Synthesis of enantiopure 2-amino-1-phenyl and 2-amino-2-phenyl ethanols using enantioselective enzymatic epoxidation and regio-and diastereoselective chemical …

G Sello, F Orsini, S Bernasconi, P Di Gennaro

Index: Sello, Guido; Orsini, Fulvia; Bernasconi, Silvana; Gennaro, Patrizia Di Tetrahedron Asymmetry, 2006 , vol. 17, # 3 p. 372 - 376

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Citation Number: 28

Abstract

Several enantiopure 1, 2-amino alcohols have been prepared by combining a stereoselective enzymatic epoxidation of styrenes with regio-and stereoselective chemical reactions. An interesting reactivity has been noted concerning the reaction of epoxides and NH3 under microwave activation.