Aglycone structure influences α-fucosyltransferase III activity using N-acetyllactosamine glycoside acceptors

…, JR Etchison, Y Ding, O Hindsgaul, HH Freeze

Index: Ding, Yili; Miura, Yoshiaki; Etchison, James R.; Freeze, Hudson H.; Hindsgaul, Ole Journal of Carbohydrate Chemistry, 1999 , vol. 18, # 4 p. 471 - 475

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Citation Number: 11

Abstract

Abstract We showed previously that Chinese hamster ovary cells took up and utilized a variety of N-acetylglucosaminides as primers of oligosaccharide biosynthesis (Ding et al., 1999, J. Carbohydr. Chem., 18: 471–475). In this study, a library of N-acetylglucosaminides was enzymatically galactosylated in vitro to yield type 2 chain N-acetyllactosaminides bearing a variety of aglycones. Those disaccharides are potential acceptors for ...