Journal of agricultural and food chemistry

Transformation of rutin to antiproliferative quercetin-3-glucoside by Aspergillus niger

HJ You, HJ Ahn, GE Ji

Index: Ju You, Hyun; Jin Ahn, Hyung; Ji, Geun Eog Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 20 p. 10886 - 10892

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Citation Number: 58

Abstract

The flavonol quercetin in plants and foods occurs predominantly in the form of glycoside whose sugar moiety affects the bioavailability and the mechanism of its biological activities. The antiproliferative activities of quercetin derivatives such as quercetin aglycone, quercetin- 3-β-d-glucoside (Q3G), and rutin were compared using six different cancer cell lines including colon, breast, hepatocellular, and lung cancer. The IC50 value of Q3G ranged ...